Chemical Risk Assessment Results

Assessment for: Acetone (CAS: 67-64-1) - Extraction Procedure

HIGH RISK

Executive Summary

Overall Risk Level: HIGH RISK - The use of 500mL acetone for extraction procedures under standard laboratory conditions presents significant hazards requiring enhanced safety measures.

Key Risk Factors:

• High flammability (Flash point: -20°C)
• Large quantity increases fire and vapor exposure risks
• Moderate toxicity with CNS depression potential
• Requires enhanced ventilation and fire prevention

Chemical Properties

Molecular Weight: 58.08 g/mol

Boiling Point: 56.05°C

Flash Point: -20°C

Vapor Pressure: 184 mmHg

NFPA Ratings

1

Health

3

Fire

0

Reactivity

Risk Factor Breakdown

Flammability Risk

85%

Toxicity Risk

45%

Reactivity Risk

15%

Quantity Factor

70%

Required PPE

Safety Goggles

Chemical splash

Lab Coat

Chemical resistant

Nitrile Gloves

Chemical resistant

Face Shield

Large quantity

Engineering Controls & Safety Recommendations

Ventilation Requirements

• Work in certified fume hood
• Minimum 100 fpm face velocity
• Ensure adequate room ventilation
• Monitor vapor concentrations

Fire Prevention

• Remove all ignition sources
• Use explosion-proof equipment
• Ground all containers
• Keep fire extinguisher nearby

Emergency Procedures

• Spill kit readily available
• Emergency shower/eyewash
• Emergency contact numbers
• Evacuation procedures posted

Critical Warnings

⚠️ Extremely flammable - keep away from heat, sparks, and flames

⚠️ Large quantity increases fire hazard significantly

⚠️ Vapors may cause drowsiness and dizziness

⚠️ Do not work alone when handling large quantities

Waste Disposal

Classification: Hazardous waste - flammable liquid

Container: Compatible, labeled waste container

Storage: Flammable waste storage area

Disposal: Licensed hazardous waste contractor

Documentation: Waste tracking forms required

Chemical Risk Assessment Tool